We surmise that results obtained from the experiments described in this section cannot serve to understand the role of I_NaL in arrhythmogenesis.

1. Van Driessche W, Lindemann B: Amount dependency regarding currents owing to unmarried salt-selective skin pores within the frog epidermis. Character. 1979; 282 (5738): 519-520 PubMed Conceptual | Blogger Complete Text

It means the newest good results submit by this manuscript is perhaps not warranted and that i do not approve the latest manuscript within this function

The newest authors enjoys made clear several of the inquiries I increased in the my prior remark. Sadly, most of the major difficulties have not been handled by this improve. While i stated in my personal early in the day feedback, We consider it unlikely that most those people facts shall be solved merely because of the several additional paragraphs. As an alternative there are specific standard questions towards fresh framework and, very critically, into studies.

It means the fresh new strong results submit through this manuscript is not justified and i also try not to agree the newest manuscript contained in this means

New people has made clear several of the questions I increased in the my past remark. Unfortunately, every major issues haven’t been managed by this modify. Once i produced in my personal early in the day remark, I deem they unlikely that every those people activities can be solved only from the several extra sentences. As an alternative there are still specific important concerns on fresh build and you can, very vitally, to the analysis.

• Best concern is that if We used the newest description off the methods in the earlier type it had been possible in order to decode, with nearly prime precision, one haphazard stimuli brands I selected. See to possess samples of which reanalysis. Whether or not we imagine the genuine stimulus looked within an after day otherwise was consistently alternating ranging from rule and you may silence, the latest decoding is close to prime. This can be an indicator that the decoding has nothing accomplish with the real stimuli heard because of the Sender but is opportunistically exploiting some other possess regarding investigation. This new handle study new experts did, treating the brand new stimulus brands, try not to address this dilemma because is suffering from the exact same problem. Fundamentally, just what classifier try allegedly having fun with is the time that has enacted just like the tape become.
• The explanation for this is exactly dissertation writer allegedly your article authors used non-independent investigation for degree and you may research. Just in case I’m sure precisely (look for point step 3), haphazard testing 1 / 2 of data samples out of a keen EEG shadow are not separate investigation. Repeated the analysis 5 times the fresh new control data the new article authors did is not a sufficient way to address so it concern. Randomly trying to find samples regarding a period of time collection which includes sluggish transform (for instance the sluggish revolution pastime one presumably dominates these recordings significantly less than these scenarios) tend to usually include good temporary correlations. Discover TemporalCorrelations.jpg set for 2D occurrence histograms and you may a relationship matrix proving so it.
• Just like the modified steps part provides greater detail today, they continues to be confused about what study were utilized. Antique group research declaration exactly what studies has (usual articles regarding research matrix) and you may exactly what findings (usual rows) were used. One thing would be a feature but usually this is certainly new various other EEG streams or fMRI voxels an such like. Findings are usually go out activities. Right here I suppose the people switched new raw samples on a beneficial additional room using principal part analysis. This is simply not said when your dimensionality was shorter using the eigenvalues. In any event, I suppose the content samples (obtained in the 128 Hz) were upcoming made use of since the observations therefore the EEG channels turned by PCA were used while the possess. The new stimulus names was indeed tasked since Towards the otherwise Out of per sample. Some 50% off trials (and you may labels) was then chosen at random to possess education, in addition to others was utilized getting comparison. Is this proper?